This project has closed. Read the final report here.

Achievements

Presentations at conferences

PresenterTitleConference
Breteau, M.Developing phage therapy to treat canine skin infection cause by Staphylococcus pseudintermediusAntimicrobial Drug Discovery conference, Madrid, ES, 06/2013
Breteau, M.Developing phage therapy to treat canine skin infection caused by Staphylococcus pseudintermediusPhages2014, Oxford, UK, 09/ 2014
Breteau, M.Developing phage therapy to treat canine skin infection caused by Staphylococcus pseudintermediusBacteriophages 2015, London, UK, 01/ 2014
Breteau, M.Study of Staphylococcus pseudintermedius phages: towards the development of phage therapyPostgraduate Symposium 2015, School of Life Sciences, University of Warwick, UK, 03/ 2015
Gaiser, R.Bacteriocins from microbiota to prevent Streptococcus suis carriage and infection in pigsTRAIN-ASAP 2nd Annual Meeting, Olot, ES, 06/ 2013
Oddo, A.Ring flexibility as a key design feature for cyclic antimicrobial peptidesAntimicrobial Peptide Symposium, Lorient, 07/2014
Wellington, E.MMining metagenomes for discovery of novel enzymes and metabolitesWorshop Exploiting microbial genomics and synthetic biology for discovery of novel antibiotics, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, CN, 12/2013
Wellington, E.MThe environment as a reservoir of antibiotic resistance and biosynthesisFunctional metagenomics South Africa invited speaker second meeting of Metagenomics Societ, SA, 06/2012
Wellington, E.M Metagenomes for bioexploration: the environmental gene pool. International Functional Metagenomics Workshop, University of Waterloo, Canada May5-7 International Functional Metagenomics Workshop, University of Waterloo, CA, 05,2012
Wellington, E.MWhat can DNA do for you? DNA technology and applications.Conference Society of Chemical Industry HQ, London, UK, 03/2012
Wellington, E.MThe role of the mobilome in transmission pathways for antibiotic resistance genes in rivers, sewage and slurries3rd International Symposium on the Environmental Dimension of Antibiotic Resistance, DE

Wellington, E.M

Host transmission to the environmentFundacion Ramon Areces International Symposium Microbiology. Madrid, ES
Wellington, E.MEnvironmental reservoirs of antibiotic resistanceat ‘Modelling transboundary diseases: A one-health approach’, Animal Plant Health Agency, Weybridge
Oddo, A:Ring flexibility as a key design feature for cyclic antimicrobial peptidesAntimicrobial Peptide Symposium, Lorient, 07/ 2014

Posters

PresenterTitleConference
Breteau, M.Developing phage therapy to treat canine skin infection caused by Staphylococcus pseudintermedius.Postgraduate Symposium 2014, School of Life Sciences, University of Warwick, UK, 03/2014
Ovejero, C. M., Hidalgo, L., Gutiérrez, B., Carrilero, L., Santos-López, A., Thomas-Lopez, D., Hoefer, A., Saba, C.S.K., Matrat, S., Santurde, G., Martin-Espada, C. and Gonzalez-Zorn, B.Tigecycline resistant Klebsiella pneumoniae from companion animals.23rdECCMID, Berlin Germany, 07/2013
Ovejero, C. M., Hidalgo, L., Gutiérrez, B., Carrilero, L., Santos-López, A., Thomas-Lopez, D., Hoefer, A., Saba, C.S.K., Matrat, S., Santurde, G., Martin-Espada, C. and Gonzalez-Zorn, B.Human Klebsiella pneumoniae ST11 and ST147 clone resistant to tigecycline from pet animals.MVNA Conference, Copenhagen, Denmark, 07/2013
Larberg, A.K.Optimize dose-regime of new veterinary macrolides.IVP Annual meeting, Copenhagen, DK, 2013
Larberg, A.K.Optimizing dose-regime of new veterinary macrolides – Development of an in vitro pharmacodynamics model.Star conference, Madrid, ES, 2013
Amos, G. and Borsetto, C.Using functional metagenomics for the discovery of new antimicrobial compounds.2nd Thünen Symposium on Soil Metagenomics, Braunschweig, DE, 12/2013
Gaiser, R.Heterologous Production of Antimicrobial Peptides by Lactic Acid Bacteria.STARS Antimicrobial Drug discovery Conference, Madrid, ES, 06/2013
Greco, I.Peptide-peptoid hybrids active against methicillin-resistant Staphylococci and Pseudomonas aeruginosa.ULLA SUMMER SCHOOL, London, UK, 07/2013
Greco, I.A novel peptide-peptoid hybrid active against methicillin resistant Staphylococcus pseudintermedius.3rd ASM-ESCMID Conference MRSA in animals, Copenhagen, DK, 11/2013.
Greco, I.AMP mimics with bactericidal activity against Staphylococci and Pseudomonas as novel drugs for topical use in veterinary medicine.4th International Symposium on Antimicrobial Peptides Lorient, 06/2014
Greco, I.Short Linear Peptide-Peptoid Hybrids as Potential Antimicrobial Drugs.24th American Peptide Symposium, Orlando 20-25, 06/2015
Oddo, A.Design of novel cyclic antimicrobial peptidesULLA Summer School, London, UK, 07/2013
Borsetto, C.Using metagenomics to explore diverse environments for novel natural product gene clustersEmerging Challenges and Opportunities in Soil Microbiology, Loughborough, UK, 09/2014
Borsetto, C.Exploring metagenomes from diverse soils for natural product gene clustersJohn Innes – Rudjer Bošković Summer Schools on Applied Molecular Microbiology “Microbial Specialised Metabolites: Origins and Applications”, Dubrovnik, HR, 09/2014
Borsetto, C.Exploring metagenomes from diverse environments for novel natural product gene clustersISBA 17, Kusadasi, TR, 10/2014
Borsetto, C.Exploring metagenomes from diverse environments for novel natural product gene clustersComMet meeting, The Shard, London, UK, 03/2015
Borsetto, C.Emerging challenges in antibiotic discovery: metagenomes from diverse environments for novel natural product gene clusters.Directing Biosynthesis IV, Norwich, UK, 03/2015
Borsetto, C.Exploring diverse environments using metagenomics for novel natural productsBAGECO, Milan, Italy, 06/2015
Baldry, M.An in vitro assessment of host immune and component interaction profile of the Staphylococcus aureus anti-virulence candidates Solonamide B and derivatives.International Symposium on Staphylococci and Staphylococcal Infections – ISSSI 2014, Chicago, USA, 08/2014
Baldry, M.Characterizing the Staphylococcus aureus anti-virulence candidate Solonamide B and its lactam analogues.FEMS 2015 6th Congress of European Microbiologists, Maastricht, NL, 06/2015.
Hoefer, A.5’ UTR mediated regulation of the emerging 16S rRNA aminoglycoside resistance methyltransferase armAFEBS-ASM WORKSHOP: Biology of RNA in host-pathogen interactions, Tenerife ES, 01/ 2014
Hoefer, A.Phenotypic changes caused by the truncation of the 5’ UTR suggest a stringent translational regulation of the aminoglycoside resistance methyltransferase ArmA X Reunión del Grupo Especializado de la SEM de Microbiología Molecular, Segovia, ES, 06/ 2014
Mutuku, I.Sequence and Comparative Analysis of Avian Pathogenic Escherichia coli Phages.Bacteriophages Conference, The O2, London, UK, 01/2015
Mutuku, I.Characterization of Avian Pathogenic Escherichia coliSfAM&MVNA Summer Conference, Brighton UK, 07/2014
Mutuku, I.Control of poultry APEC outbreaks by Phage Therapy.STARS Antimicrobial Drug Discovery Conference, Madrid, ES, 06/2013
Cruz, J.Discovery of new antimicrobial candidates from actinoallomurusVAAM meeting, Dresden, DE, 10/2014
Cruz, J.Discovery of new antimicrobial candidates from actinoallomurusFEMS meeting, Maastrich, NL, 06/2015
Sadaka, C., Guardabassi, L., Kanellos, T., Sweeney, M.T. and Watts, J. L.Determination of Optimal In vitro Drug Ratios of Trimethoprim/Sulfamethoxazole and Trimethoprim/Sulfadiazine Against Equine Pathogens.American Association of Veterinary Laboratory Diagnostics ,57th Annual Conference Proceedings, Kansas City MO, USA, 10/2014

Publications

AuthorsTitleJournalVolume/Issue)DatePagesPeer reviewed
Hidalgo, L, Gutierrez, B., Ovejero, C.M., Carrilero, L., Matrat, S., Saba, C.K., Santos-Lopez, A., Thomas-Lopez, D., Hoefer, A., Suarez, M., Santurde, G., Martin-Espada, C. and Gonzalez-Zorn, B.Klebsiella pneumoniae sequence type 11 from companion animals bearing ArmA methyltransferase, DHA-1 β-lactamase, and QnrB4.Antimicrobial Agents and Chemotherapy57(9)09/20134532-4534
Pontiroli, A., Khera, T.T., Oakley B. B., Mason S., Scot E. Dowd S. E., Travis E. R., Erenso G., Abraham Aseffa A., Orin Courtenay, O. and Wellington E.M.Prospecting Environmental Mycobacteria: combined molecular approaches reveal unprecedented diversity.PLOS ONE8(7)07/2013E68648Yes
Pearce, D.A., Newsham, K.K., Thorne, M.A., Calvo-Bado, L., Krsek, M., Laskaris, P., Hodson, A. and Wellington, E.M.Metagenomic analysis of a southern maritime antarctic soil.Frontiers in Microbiology3(403)12/20121-13Yes
Selama, O., Amos, G.C.A., Djenane, Z., Borsetto, C., Forar Laidi, R., Porter, D., Nateche, F., Wellington, E.M.H. and Hacène, H.Screening for Genes Coding for Putative Antitumor Compounds, Antimicrobial and Enzymatic Activities from Haloalkalitolerant and Haloalkaliphilic Bacteria Strains of Algerian Sahara Soils.Biomed Res Int. 20142014: 31752405/20141-11Yes
Kitir, B., Baldry, M., Ingmer, H., and Olsen, C.A.Total synthesis and structural validation of cyclodepsipeptides solonamide A and B.Tetrahedron70(42)10/20147721-7732Yes
Oddo, A., Münzker, L. and Hansen, P.R.Peptide Macrocycles Featuring a Backbone Secondary Amine: A Convenient Strategy for the Synthesis of Lipidated Cyclic and Bicyclic Peptides on Solid Support.Organic Letters17(10)05/20152502-05Yes